HIPEC and PIPAC: Innovative Treatments for Advanced Abdominal Cancers

Posted on Sept. 22, 2025, 11:36 a.m. by Dr Ramkishan Nag
hipec-and-pipac-innovative-treatments-for-advanced-abdominal-cancers

HIPEC and PIPAC: Innovative Treatments for Advanced Abdominal Cancers

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) and Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) represent significant advancements in the treatment of advanced abdominal cancers, particularly those affecting the peritoneum. These innovative procedures offer hope and improved outcomes for patients facing peritoneal malignancies, conditions where cancer cells have spread within the abdominal cavity. By directly targeting the cancer cells in the peritoneum, HIPEC and PIPAC can provide a more effective approach compared to traditional systemic chemotherapy alone.

HIPEC involves surgically removing visible tumors from the abdominal cavity, followed by the circulation of heated chemotherapy solution directly within the peritoneum. The heat enhances the effectiveness of the chemotherapy drugs, allowing them to penetrate and destroy remaining cancer cells more efficiently. This localized treatment minimizes systemic side effects, as the chemotherapy is primarily contained within the abdominal cavity. HIPEC is often used for cancers that have spread to the peritoneum from the colon, ovaries, or other abdominal organs.

PIPAC, on the other hand, utilizes a minimally invasive laparoscopic approach to deliver chemotherapy in aerosol form directly into the abdominal cavity. The pressurized aerosol allows for a more even distribution of the chemotherapy drugs, reaching areas that might be difficult to access with traditional methods. PIPAC is particularly useful for patients with heavily diseased peritoneums where surgical removal of tumors may not be feasible. It can help control cancer growth, alleviate symptoms, and potentially improve quality of life.

Dr. Ramkishan Nag, a highly skilled Surgical Oncologist based in Mumbai, offers these cutting-edge procedures to his patients. With over a decade of experience and over 5,000 cancer surgeries to his credit, Dr. Nag is dedicated to providing world-class oncology care in India. His expertise spans a wide range of cancers, including gastrointestinal, colorectal, liver, pancreatic, gynecologic, and breast cancers, and he is trained in advanced laparoscopic and robotic techniques, as well as HIPEC and PIPAC.

Dr. Nag's practice, located at 1st Floor, Urban Grandeur, Kanakia, Mira Road 401105 in Mumbai, Maharashtra, is committed to ethical, evidence-based treatment. He strives to make advanced cancer care accessible and affordable, combining medical excellence with genuine compassion. By offering innovative treatments like HIPEC and PIPAC, Dr. Nag provides his patients with the best possible chance for a positive outcome, emphasizing faster recovery, minimal scarring, and organ-preserving options.

About Dr Ramkishan Nag
I am a highly skilled Surgical Oncologist with more than a decade of experience and over 5,000 cancer surgeries to my credit. I specialize in advanced laparoscopic and robotic techniques, offering patients faster recovery, minimal scarring, and organ-preserving options. My expertise spans gastrointestinal, colorectal, liver, pancreatic, gynecologic, and breast cancers.

Trained at the renowned Tata Memorial Hospital, Mumbai, and in cutting-edge procedures such as HIPEC and PIPAC, I bring global standards of cancer care to India. I am committed to ethical, evidence-based treatment and strive to make world-class oncology care accessible and affordable for every patient, combining medical excellence with genuine compassion.
Ethical Cancer Care: Prioritizing Patient Well-being and Evidence-Based Treatment
September 25, 2025 |

Ethical Cancer Care: Prioritizing Patient Well-being and Evidence-Based Treatment

Read more →
Navigating Cancer Treatment: A Patient's Guide
September 22, 2025 |

Navigating Cancer Treatment: A Patient's Guide

Read more →
Organ-Preserving Surgery: Maximizing Cancer Treatment While Minimizing Impact
September 21, 2025 |

Organ-Preserving Surgery: Maximizing Cancer Treatment While Minimizing Impact

Read more →
Dr Ramkishan Nag contact